About “fretub PREMIUM” 30.6 billion lactic acid bacteria

fretub PREMIUM

Why heat sterilization?

  • Many bacterial strains 22 types of lactic acid bacteria, containing more than 100 billion heat-sterilized lactic acid bacteria per gram. You can appeal many bacterial species and many bacterial counts just by blending a small amount.
  • Usability during manufacturing Because it is a sterilized body, there is no concern about contamination during each process such as processing, manufacturing, storage, and transportation.
  • Excellent stability Stable quality and properties during manufacturing, storage and transportation.
  • High versatility High heat resistance, suitable for processing where heat is applied. It can be applied to a wide range of processed foods without limiting dosage forms (tablets, granules, etc.) or food types (baked confectionery, bakery, etc.).

Introduction of 22 fungi

Contains 5 types of bifidobacteria and 17 types of lactic acid bacteria in an optimal ratio.


It is known to regulate the human intestinal environment as a “good bacteria”.

This medicine produces acetic acid and lactic acid in the intestine, keeps the pH in the intestine low, and suppresses the number of opportunistic infectious bacteria such as Escherichia coli.
It has also been reported to have anti-infection, immunostimulatory and cholesterol-lowering effects.

It is known that the type and number of bifidobacteria in the intestine change with age, and that the total number of bifidobacteria decreases significantly in the elderly.

We selected 5 influential bifidobacteria, infantis and breve known as infantiles, and longum, which lives from infants to the elderly.

Species name

  • Bifidobacterium animalissubsp.lactis
  • Bifidobacterium bifidum
  • Bifidobacterium breve
  • Bifidobacterium infantis
  • Bifidobacterium longum


Lactobacillus is a rod-shaped bacterium that produces lactic acid.
Cheese and fermented milk made by fermentation of Lactobacillus have long been used as preserved foods.

Recent research has revealed health effects such as intestinal regulation, infection prevention, immunostimulation, and allergy reduction, and research is also progressing on the mechanism of action.

Species name

  • Lactobacillus acidophilus
  • Lactobacillus buchneri
  • Lactobacillus casei
  • Lactobacillus delbrueckiisubsp.bulgaricus
  • Lactobacillus delbrueckiisubsp.lactis
  • Lactobacillus fermentum
  • Lactobacillus gasseri
  • Lactobacillus johnsonii
  • Lactobacillus paracasei
  • Lactobacillus plantarum
  • Lactobacillus reuteri
  • Lactobacillus rhamnosus
  • Lactobacillus salivarius


Enterococcus, Lactococcus, and Streptococcus are ball-shaped cocci (coccus). Those that belong to the intestinal group are called entero (intestinal tract-derived) coccus, those that belong to the lactic acid group are called lacto (lactic acid-producing) coccus, and those that are linked like a chain are called streptococci.

The diameter of one coccus is usually 0.6 to 1.0 μm, which is a microscopic size that is advantageous for uptake in the intestinal tract.
In addition to its intestinal regulation effect, it is also expected to have an immunostimulatory effect.

Species name

  • Enterococcus faecium
  • Lactococcus lactissubsp.cremoris
  • Lactococcus lactis subsp.lactis
  • Streptococcus thermophilus